| アイテムタイプ |
研究者データベースシステム連携 / Researcher Database System(1) |
| 公開日 |
2026-03-09 |
| タイトル |
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|
タイトル |
Regeneration of tunic cuticle is suppressed in edible ascidian Halocynthia roretzi contracting soft tunic syndrome |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Azumiobodo hoyamushi |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Ultrastructure |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
MCA substrate assay |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Protease |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
RNA-seq |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
NAKAYAMA, Kei
| en |
NAKAYAMA, Kei
|
| ja |
Center for Marine Environmental Studies (CMES), Ehime University
|
Search repository
OBAYASHI, Yumiko
| en |
OBAYASHI, Yumiko
Center for Marine Environmental Studies (CMES), Ehime University
|
Search repository
MUNECHIKA, Leo
| en |
MUNECHIKA, Leo
Center for Marine Environmental Studies (CMES), Ehime University
|
Search repository
KITAMURA, Shin-Ichi
| en |
KITAMURA, Shin-Ichi
Graduate School of Bioresources, Mie University
|
Search repository
YANAGIDA, Tetsuya
| en |
YANAGIDA, Tetsuya
Joint Faculty of Veterinary Medicine, Yamaguchi University
|
Search repository
HONJO, Miho
MURAKAMI, Shoko
| en |
MURAKAMI, Shoko
|
| ja |
Center for Marine Environmental Studies (CMES), Ehime University
|
Search repository
HIROSE, Euichi
| en |
HIROSE, Euichi
Department of Chemistry, Biology, and Marine Science, Faculty of Science, University of the Ryukyus
|
Search repository
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| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Soft tunic syndrome is an infectious disease caused by the flagellate Azumiobodo hoyamushi, which severely damages the aquaculture of the edible ascidian Halocynthia roretzi. Tunic is a cellulosic extracellular matrix entirely covering the body in ascidians and other tunicates, and its dense cuticle layer covers the tunic surface as a physical barrier against microorganisms. When the tunic of intact H. roretzi individuals was cut into strips, electron-dense fibers (DFs) appeared on the cut surface of the tunic matrix and aggregated to regenerate a new cuticular layer in seawater within a few days. DF formation was partially or completely inhibited in individuals with soft tunic syndrome, and DF formation was also inhibited by the presence of some proteases, indicating the involvement of proteolysis in the process of tunic softening as well as cuticle regeneration. Using pure cultures of the causative flagellate A. hoyamushi, the expression of protease genes and secretion of some proteases were confirmed by RNA-seq analysis and a 4-methylcoumaryl-7-amide substrate assay. Some of these proteases may degrade proteins in the tunic matrix. These findings suggest that the proteases of A. hoyamushi is the key to understanding the mechanisms of cuticular regeneration inhibition and tunic softening. |
|
言語 |
en |
| 書誌情報 |
en : Diseases of Aquatic Organisms
巻 159,
p. 37-48,
発行日 2024-08-01
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| 出版者 |
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出版者 |
Inter-Research Science Publisher |
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言語 |
en |
| ISSN |
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|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0177-5103 |
| 書誌レコードID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10443976 |
| PubMed番号 |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
PMID |
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|
関連識別子 |
39087618 |
| DOI |
|
|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3354/dao03801 |
| 権利情報 |
|
|
権利情報Resource |
https://creativecommons.org/licenses/by/4.0/ |
|
権利情報 |
Creative Commons Attribution 4.0 International |
|
言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
Accepted Manuscript_AA10443976_159_37-48.pdf (5.6 MB)
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