| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-03-19 |
| タイトル |
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|
タイトル |
A case of hepatocellular carcinoma with pseudoaneurysm formation upon lenvatinib administration |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Hepatocellular carcinoma |
| キーワード |
|
|
言語 |
en |
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主題Scheme |
Other |
|
主題 |
Lenvatinib |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Pseudoaneurysm |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Micro B-flow imaging |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Contrast-enhanced ultrasonography |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
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|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
YANO, Ryo
| en |
YANO, Ryo
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
|
Search repository
HIROOKA, Masashi
| en |
HIROOKA, Masashi
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
|
Search repository
NAKAMURA, Yoshiko
| en |
NAKAMURA, Yoshiko
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
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Search repository
IMAI, Yusuke
| en |
IMAI, Yusuke
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
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Search repository
KOIZUMI, Yohei
| en |
KOIZUMI, Yohei
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
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Search repository
WATANABE, Takao
| en |
WATANABE, Takao
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
|
Search repository
YOSHIDA, Osamu
| en |
YOSHIDA, Osamu
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
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Search repository
TOKUMOTO, Yoshio
| en |
TOKUMOTO, Yoshio
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
|
Search repository
ABE, Masanori
| en |
ABE, Masanori
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
|
Search repository
HIASA, Yoichi
| en |
HIASA, Yoichi
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
|
Search repository
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| 抄録 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
A 79-year-old man received treatment for multiple intrahepatic hepatocellular carcinoma with atezolizumab + bevacizumab. However, he developed lower back pain attributed to spinal metastases upon tumor enlargement; thus, he was admitted to our hospital for a change from atezolizumab + bevacizumab to lenvatinib and radiation therapy for the spinal metastases. On the 11th day after starting lenvatinib treatment, a pulsatile aneurysm appeared in the tumor, detected using abdominal ultrasonography Micro B-flow imaging, which visualized blood flow at a high frame rate; this was diagnosed as a pseudoaneurysm. The patient refused treatment for the pseudoaneurysm; therefore, he was carefully followed up. Fortunately, the pseudoaneurysm disappeared on the 17th day. One month later, the tumor had become completely necrotic. Lenvatinib demonstrated effectiveness in inhibiting angiogenesis in the tumor, as evidenced by a decrease in tumor blood flow. This case report suggests that pseudoaneurysm formation within the tumor occurs early after the administration of lenvatinib; thus, clinicians must be aware of the potential risk of pseudoaneurysm rupture. |
|
言語 |
en |
| 書誌情報 |
en : Clinical Journal of Gastroenterology
巻 17,
号 2,
p. 319-326,
発行日 2024-04
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| 出版者 |
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出版者 |
Springer Nature |
|
言語 |
en |
| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1865-7257 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA12646624 |
| PubMed番号 |
|
|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
PMID |
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|
関連識別子 |
38281290 |
| DOI |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1007/s12328-023-01914-7 |
| 権利 |
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|
権利情報 |
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s12328-023-01914-7 |
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言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
Accepted Manuscript_AA12646624_17_319-326.pdf (375 KB)
Fig.zip (42.8 MB)
