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Heavy oil fraction induces the dysplastic sperm in male mouse
https://ehime-u.repo.nii.ac.jp/records/2002272
https://ehime-u.repo.nii.ac.jp/records/20022726f4a091b-d24f-40f8-886f-06366e8e3f4f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00002808_36_487.pdf
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2012-02-20 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Heavy oil fraction induces the dysplastic sperm in male mouse | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Heavy oil | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Water-soluble fraction (WSF) | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Oral administration | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Breeding | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Spermatogenesis | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Sperm | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Testosterone | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | journal article | |||||||||||||||
| 著者 |
NISHIMOTO, Sogo
× NISHIMOTO, Sogo
× AKIYAMA, Koichi
× KAKINUMA, Yoshimi
× KITAMURA, Shin-Ichi
× SUGAHARA, Takuya
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| 抄録 | ||||||||||||||||
| 内容記述 | Heavy oil is one of the most serious pollutants in marine ecosystem. The poisonous influences of the chemical substances contained in heavy oil on many kinds of marine organisms are widely studied. However, the influence of the chemical compounds in heavy oil on our health has not been cleared yet. In order to reveal the poisonous influences of these chemical compounds on mammalian reproductive system, water-soluble fraction (WSF) extracted from heavy oil was administrated to mice for 2 weeks. WSF-administrated mice were crossed with either WSF- or distilled water-administrated group for mating experiment. When WSF-administrated male mice were used as a father, it reduced not only mating ratio, but also neonatal male ratio. The numbers of sperms of WSF-administrated male mice were decreased. In addition, abnormality of sperms such as bent or twisted tail was increased approximately 6-fold by WSF intake. The level of testosterone in serum from WSF-administrated mice was lower than that from control mice. Testosterone is the most important for the spermatogenesis in vertebrate. It is supposed from these findings, the decrease in the number of sperms may relate with the reduction of sex hormone level in serum. It is suggested from these results that the chemical substances in WSF affected the sperm function in reproductive system of male mice. | |||||||||||||||
| 言語 | en | |||||||||||||||
| 書誌情報 |
en : The Journal of Toxicological Sciences 巻 36, 号 4, p. 487-491, 発行日 2011-08 |
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| 出版者 | ||||||||||||||||
| 出版者 | The Japanese Society of Toxicology | |||||||||||||||
| 言語 | en | |||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||||
| 収録物識別子 | 0388-1350 | |||||||||||||||
| 書誌レコードID | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AN00002808 | |||||||||||||||
| PubMed番号 | ||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||
| 関連識別子 | 21804313 | |||||||||||||||
| DOI | ||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||
| 関連識別子 | 10.2131/jts.36.487 | |||||||||||||||
| 著者版フラグ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
| 日本十進分類法 | ||||||||||||||||
| 主題Scheme | NDC | |||||||||||||||
| 主題 | 491.5 | |||||||||||||||
